Antimicrobial prescribing: NHS Borders
Important: Therapy
See NHS Borders Sexual Health STI protocol http://www.borderssexualhealth.org.uk/for-professionals/clinical-protocols/
Epididymo-orchitis
Important: Therapy
First line
Trimethoprim 200mg oral 12 hourly for 14 days
or
Second line
Ofloxacin 200mg oral 12 hourly for 14 days
Consider safety issues with quinolones.
Review at 14 days. If symptoms persist, for further course of antimicrobial treatment
Notes:
Important: Therapy
Amoxicillin 500mg-1g IV 8 hourly
+
Gentamicin IV (Extended interval dosing as per guideline. Use gentamicin calculator. Max 3 days then review.
Notes:
Important: Notes
All sexually active men should be tested for Chlamydia and Gonorrhoea (urine sample for NAAT testing) prior to treatment
See NHS Borders Sexual Health STI protocols for more details http://www.borderssexualhealth.org.uk/for-professionals/clinical-protocols/
Fluroquinolones
Refer to important safety information for all quinolones prior to prescribing.
See MHRA Drug Safety Update January 2024: Fluoroquinolones must only be used in situations when other antibiotics, that are commonly recommended for the infection, are inappropriate such as:
- there is resistance to other first-line antibiotics recommended for the infection
- other first-line antibiotics are contraindicated in an individual patient
- other first-line antibiotics have caused side effects in the patient requiring treatment to be stopped
- treatment with other first-line antibiotics has failed