Important: Therapy
Amoxicillin 1g IV 8 hourly
+
Gentamicin IV (Extended Interval Dosing as per guideline) Use gentamicin calculator. Max 3 days then review.
If MRSA suspected substitute Vancomycin IV (Dosing as per guideline. Use vancomycin calculator) for amoxicillin.
If intra-abdominal source suspected see Gastro-Intestinal Tract Infections – Intra-Abdominal Sepsis
Change according to results of sensitivities. Switch to oral as soon as appropriate.