Intra-abdominal infections

Oral

COTRIMOXAZOLE PO 960mg BD (eGFR>35 ml/min)

Plus

METRONIDAZOLE PO 400mg TDS

Or

DOXYCYCLINE PO 200mg OD

Plus

METRONIDAZOLE PO 400mg TDS

Intravenous

AMOXICILLIN IV 1g TDS

Plus

GENTAMICIN IV Dose as per calculator

Plus

METRONIDAZOLE PO 400mg TDS (If PO route is not available, use IV 500mg TDS) (PO METRONIDAZOLE is as good as IV if oral route available)

If IV treatment is still needed after three days, convert GENTAMICIN to:

TEMOCILLIN IV 2g TDS

True penicillin allergy: Discuss with Microbiology

Switch to oral when able.

Duration: Depends on eventual diagnosis. Usually 5-7 days.