Community-acquired LRTI/Pneumonia (community onset without hospital admission ≥5 days in previous 4 weeks)

Important: Therapy

i) Amoxicillin 500mg-1g PO 8 hourly

 

ii) Doxycycline 200mg PO STAT then 100mg daily

 

iii) Clarithromycin 500mg PO 12 hourly

Notes:

If oral route compromised:

Ceftriaxone 2g IV 24 hourly

Important: Therapy

Try different first line agent initially if persistent signs of infection but haemodynamically stable

or if felt deteriorating infection but not severe:

Co-trimoxazole 960mg PO/IV 12 hourly 

Notes:

Important: Therapy

Ceftriaxone 2g IV 24 hourly

or if severe penicillin allergy:

Levofloxacin 500mg PO/IV 12 hourly (consider safety issues)

 

Notes:

Essential to confirm CrCl in this patient group: if CrCl <50ml/min maximum dose of levofloxacin 250mg PO/IV 12 hourly