Important: Therapy
- Serious emergency – infection of soft tissue behind orbital septum.
- Contact specialist for advice if there is evidence of intracranial extension or if the patient has had surgery.
test announcement
Streptococcus spp., Staphylococcus aureus
10 days but seek specialist advice
IV Ceftriaxone 2g 12 hourly
+ Oral Metronidazole 400mg 8 hourly (or IV 500mg 8 hourly if oral route not available)
For 10 days total treatment – if intracranial pathology excluded and patient responds well to IV, then switch after 3-5 days to
Oral Co-amoxiclav 625mg 8 hourly
IV Co-trimoxazole* 960mg 12 hourly
+ IV Clindamycin 300mg 6 hourly
For 10 days total treatment - If intracranial pathology excluded and patient responds well to IV, then switch after 3-5 days to
Oral Co-trimoxazole 960mg 12 hourly
+ Oral Clindamycin 300mg 6 hourly
*If IV Co-trimoxazole not available use IV Ciprofloxacin 400mg twice daily