Infective Exacerbation of COPD/Exacerbation of chronic bronchitis

Important: Therapy

• Collect sputum

Notes:

Give antibiotics if patient has a history of COPD and both the following are present;

• Development of purulent sputum (dark green, not yellow)
• WBC is >10 x 10⁹/L and/or CRP is elevated

Use first line antibiotic unless recent hospitalisation or recent antibiotic.

Important: Therapy

Oral Amoxicillin 1g 8 hourly

Notes:

Important: Therapy

 Oral Doxycycline 200mg on day 1 then 100mg daily

Notes:

Important: Therapy

IV Co-trimoxazole 960mg 12 hourly

then switch to oral Co-trimoxazole 960mg 12 hourly

OR

Oral Doxycycline 200mg oral stat then 100mg 12 hourly

Notes:

Important: Therapy

Oral/IV Clarithromycin 500mg 12 hourly

Notes: