Duration

4-6 weeks. Duration of treatment depends on organism, patient characteristics, presence of prosthetic valve etc.

Native Valve Endocarditis (NVE)

Important: Therapy

IV Flucloxacillin
+ IV Amoxicillin
+ IV Gentamicin

Notes:

Native Valve Endocarditis (NVE) - in penicillin allergy

Important: Therapy

IV Vancomycin 
+ IV Gentamicin

Notes:

Intra-cardiac prothesis

Important: Therapy

IV Vancomycin
+ oral Rifampicin
+ IV Gentamicin

Notes:

Important: Notes

Always take blood for culture before starting treatment for endocarditis - take a minimum of 3 separate blood cultures.

Consult a cardiologist immediately.

Consult with paediatric infectious diseases specialist and medical microbiologist about organism specific therapy and consider need for urgent surgical intervention.