Appendicitis/Peritonitis/ Penetrating abdominal trauma

Antimicrobial prescribing: NHS Grampian, Orkney & Shetland
NHS Grampian

Micro Organisms

Coliforms, anaerobes

Duration

3-7 days depending on degree of contamination and established infection.

 

First Line

Therapy

IV Metronidazole
+ IV Gentamicin
+/- IV Amoxicillin 


Switch to oral Co-amoxiclav

Notes:

Penicillin Allergy

Therapy

IV Clindamycin 
+ IV Gentamicin


For oral switch seek advice from duty medical microbiologist.

Notes:

Notes

Send blood for culture, 2 sets if possible, and pus from operation.

Oral switch may not be required depending on duration of IV therapy.