Daptomycin IV

Permitted indications

Only on the advice of a Medical Microbiologist or Infection Specialist:

1. For Staphylococcus aureus bacteraemia associated with right-sided infective endocarditis (RIE) or with complicated skin and soft tissue infection (SSTI) in adults.
2. For the (off-label) treatment of Staphylococcus aureus bacteraemia, not associated with RIE or SSTI, in penicillin allergic patients.
3. As an alternative to linezolid for the second-line treatment of complicated MRSA skin and soft tissue infection.
4. For the treatment of serious MRSA infection after glycopeptide treatment failure or if increased doses of glycopeptides cause nephrotoxicity.