Treatment duration = IV + oral = 7 days
Recommended Antibiotic |
Cefotaxime 2g every 8 hours IV AND Metronidazole 400mg every 8 hours orally (500mg every 8 hours IV if oral route not available) Severe sepsis with hypotension ADD Gentamicin as per NHS Lothian intranet calculator if on or after day 3 post partum otherwise follow guidance on Sepsis in Obstetrics guideline. AND Clindamycin 600mg every 6 hours IV |
Penicillin allergy |
Clindamycin 600mg every 6 hours IV AND Gentamicin as per NHS Lothian intranet calculator if on or after day 3 post partum otherwise follow guidance on Sepsis in Obstetrics guideline. |
MRSA positive
- Add vancomycin using NHS Lothian AMT intranet calculator choose trough level of 15-20mg/ml.
Cefotaxime and clindamycin are associated with C.diff infection.