Antimicrobial prescribing: NHS Lothian
- Send a urine sample and blood for culture
Upper urinary tract infection/pyelonephritis in pregnancy
The diagnosis is made with evidence of systemic infection e.g. fevers, rigors, back pain, and vomiting.
- Review Sepsis in Obstetrics guideline on the intranet
Recommended total duration: 14 days
| Recommended Antibiotic | Cefuroxime 1.5g every 8 hours IV |
| Penicillin anaphylaxis or cephalosporin allergy | Gentamicin use NHS Lothian AMT calculator on the intranet if day 3 or more postpartum otherwise follow Sepsis in Obstetrics guideline |
Change to oral therapy when the patient is able to tolerate oral medication.
Choose oral antibiotics based on microbiological sensitivities.
Do not use nitrofurantoin to treat a systemic infection; effective blood and kidney concentrations are not achieved.