Infection indications for intravenous immunoglobulin

Full guidance available for Infection indications for IV Immunoglobulin (IVIG) available in PDF resource. Use of IVIG must be agreed by both a microbiology consultant and a critical care consultant. Summary of infection indication and dosing for IVIG below:

• Staphylococcal and Streptococcal toxic shock syndrome (2g/kg as a single dose. No repeat doses should be given).

• Necrotising (Panton-Valentine Leukocidin associated) staphylococcal sepsis

• Severe or recurrent clostridioides difficile infection (CDI) colitis (0.4g/kg as a single dose which can be repeated)