Endocarditis

Important: Therapy

Amoxicllin IV 2g four hourly
+

Gentamicin (See synergistic gentamicin guidance)

Notes:

Important: Therapy

Flucloxacillin IV 2g six hourly (four hourly if >85kg)

Notes:

Important: Therapy

Vancomycin IV (dosing as per guideline)
+

 Gentamicin (See synergistic gentamicin guidance)

+
When therapeutic vancomycin levels reached add Rifampicin PO 600mg twice daily

Notes:

Always check for interactions with rifampicin.