Influenza
NHSL Antimicrobial Guidelines
Annual vaccination is essential for all those ‘at risk’ of influenza.
GPs may only prescribe antiviral medicines for the prophylaxis and treatment of influenza under the General Medical Services (GMS) regulations when the Chief Medical Officer (CMO) has confirmed that influenza is circulating in the community.
Antivirals are not recommended for healthy adults. Treat ‘at risk’ patients when influenza is circulating in the community, or in a care home where influenza is likely. Ideally treat within 48 hours of onset (or within 36 hours for zanamivir treatment in children).
At risk: pregnant (including up to two weeks post-partum), children under 6 months, adults 65 years or older, chronic respiratory disease (including COPD and asthma), significant cardiovascular disease (not hypertension), severe immunosuppression, diabetes mellitus, chronic neurological, renal or liver disease, morbid obesity (BMI ≥ 40).
Drug details
Drug
Resistance to oseltamivir or severe immunosuppression:
Zanamivir
Dosage
10mg
Duration
twice daily (2 inhalations by diskhaler for up to 10 days).
See Public Health England Influenza guidance for treatment of patients under 13 years or in severe immunosuppression.