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- Although most of the medications in this case have a clear indication, the cumulative effect is an enormous drug burden with pernicious ADR potential. Careful consideration is required to balance the potential for benefit for this patient versus a reasonable estimation of life expectancy
- Consideration of potential adverse impact of high drug burden on other vital areas, such as nutrition
- Strong potential for inadvertent high risk co-prescription for patients on such a long list of medications
- Difference in risk between trial populations and frail elderly
- Likely to have intercurrent illnesses and stressors requiring acute therapeutic review
- Review management of COPD
- Opportunity costs and potential savings are significant
- This complex medication regimen is likely to put strain on the carer as well as patient, affecting the health of the household
Polypharmacy guidance: realistic prescribing
