Definitions and abbreviations
Definitions
Biofilm: a slime-enclosed community of bacterial colonies that is very difficult to eradicate even with the most powerful antibiotics or sterilising systems.37
Ecthyma: a pus forming, ulcerating and crusting inflammatory skin disease.38
Endotoxin: a toxin produced by certain bacteria and released upon destruction of the bacterial cells.39
Ex vivo: in an artificial environment outside a living organism.40
Furunculosis: a condition in which the patient suffers from recurrent episodes of boils.41
Hepatalgia: pain in the liver.42
Hidradenitis: inflammation of a sweat gland.43
Lytic: of or relating to lysis; the destruction of a living cell by disruption of its membrane.44
Paronychia: infection of the skin fold at the base or side of the nail.45
Pyoderma: a pus containing skin infection.46
Sycosis vulgaris: a chronic inflammation of the hair follicles, especially of the beard, characterised by eruption of pimples and nodules.47
Abbreviations
| ARLG | Antibacterial Resistance Leadership Group |
| CPI | consumer price index |
| CS | case studies |
| DFI | diabetic foot infection |
| DFU | diabetic foot ulcer |
| DNA | deoxyribonucleic acid |
| ESKAPE | Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baummannii, Pseudomonas aeruginosa, and Enterobacter species |
| FRI | fracture-related infection |
| GMP | Good Manufacturing Process |
| GRADE | Grading of Recommendations, Assessment, Development and Evaluations |
| ICER | incremental cost effectiveness ratio |
| LEA | lower extremity amputation |
| MHRA | Medicines and Healthcare Products Regulatory Authority |
| NA | not applicable |
| NHS | National Health Service |
| NICE | National Institute of Health and Care Excellence |
| NR | not reported |
| OBS | observational trial |
| PFU | plaque forming units |
| PJI | periprosthetic joint infection |
| PSSRU | Personal and Social Services Research Unit |
| PT | phage therapy |
| QALY | quality-adjusted life-year |
| RCT | randomised controlled trial |
| SHTG | Scottish Health Technologies Group |
| SoC | standard of care |