Synergistic Gentamicin for Endocarditis in adults (426)
Warning
ALL patients with suspected or proven infective endocarditis (IE) should be discussed with microbiology or Infectious Diseases (ID) within 72 hours of starting antibiotic therapy AND re-discussed after 2 weeks if continuation of gentamicin is being considered.
Synergistic gentamicin is recommended in the initial empirical treatment of endocarditis and for some particular endocarditis pathogens, in accordance with national guidelines. When treating a patient with IE remember to consider resistance, clinical response, toxicity and suitability for outpatient parenteral antibiotic therapy (OPAT).