Hepatitis B Reactivation (891)

Hepatitis B virus reactivation (HBVr) refers to the abrupt increase in hepatitis B virus in patients with minimally active or resolved/cleared HBV infection. The loss of HBV immune control can lead to an increase in or the reappearance of HBV DNA and a rise in ALT. Liver damage due to HBVr may occur during immunosuppression and/or following immune reconstitution. HBVr may be subclinical or rarely may progress to liver failure or death despite antiviral therapy.

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Editorial Information

Last reviewed: 14/06/2024

Next review date: 13/06/2027

Author(s): David Bell.

Version: 2

Author email(s): david.bell@ggc.scot.nhs.uk.

Approved By: GGC Viral Hepatitis Managed Clinical Network

Reviewer name(s): David Bell.

Document Id: 891