Anticholinergics: These include antidepressants, overactive bladder meds, antihistamines, anti-emetics.
See: Anticholinergics | Right Decisions (scot.nhs.uk)
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- Check that the indication is still relevant.
- These medicines increase the risk of cognitive impairment, blurred vision and drowsiness. Toxicity is often the cumulative effect of several of these medicines.
- Check the full list of medicines that the patient is prescribed, and if an anticholinergic burden (ACB) score has been calculated: ACB calculator
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- Consider effectiveness and necessity.
- Optimise emollients for dry, itchy skin.
- Calculate ACB score.
- Discuss rationalising medicines on ward round.
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Analgesics
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- Check that the indication is still relevant.
- Is pain relief being achieved with the current prescription or is a review required?
- Consider GI protection if NSAIDS are prescribed, and ensure that renal function has been checked.
- If opioids are prescribed, ensure that the duration is limited and laxatives are prescribed.
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- Avoid opioids where possible, including tramadol in older adults.
- Stop NSAID if AKI, hypotension or D&V.
- Review on ward round.
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Atypical Analgesics:
Eg: amitriptyline, duloxetine, gabapentin, pregabalin.
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- Check that the indication is still relevant.
- These medicines can cause neuropsychiatric side effects and hypotension.
- Look for low BP and orthostatic hypotension.
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- Consider indication and dose reduction but avoid abrupt withdrawal.
- Ensure review on ward round.
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Antibiotics
Eg: gentamicin.
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Anticoagulants
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- Check that the indication is still relevant.
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- Consider withholding if head injury or active bleeding, unless for metal valve or recent or high risk recurrent PE.
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Anticonvulsants
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- These medicines can cause sedation, disorientation and impaired balance.
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- These are time critical medicines. Do not withhold unless immediate concern.
- Ensure relevance but do not stop abruptly without consultant discussion.
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Antidepressants
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- Check that the indication is still relevant.
- Check that there has been a timely review with initial prescriber.
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Antipsychotics
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- Check that the indication is still relevant.
- Check what the indication is, do antipsychotics have a role and have they been regularly reviewed for efficacy?
- Are there symptoms of distress and what are the trigger factors for distress?
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- Avoid abrupt withdrawal, but consider clinical need and discuss dose alterations with MHLT.
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Benzodiazepines and Z drugs.
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- Check that the indication is still relevant.
- Review indication and dose.
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- Avoid abrupt withdrawal but review clinical need and benefit on ward round.
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Bladder medicines
Eg: tamsulosin, solifenacin, tolterodine.
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- Check that the indication is still relevant.
- Look for low BP and orthostatic hypotension.
- Is there evidence of efficacy documented?
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- Has patient been catheterised since admission?
Keep, if planning to remove catheter.
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Blood pressure lowering drugs
Eg: ACE Inhibitors, alpha blockers, diuretics.
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- Check that the indication is still relevant.
- Look for BP consistently <140/80mmHg.
- Is there evidence of AKI or electrolyte imbalance?
- Obtain a lying and standing BP.
- Does the patient suffer dizziness on standing?
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- Consider indication and withhold if possible.
- Review dose if AKI.
- Review on ward round.
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Eye treatments
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- Risk of blurred vision if not administered.
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- Check time of prescribing.
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Hypoglycaemics |
- Check that the indication is still relevant.
- Are BMs <6
- Recent HbA1C
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- Withhold sulphonylurea if BMs <6.
- Involve Diabetes Specialist Nurse.
- Review on ward round.
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Muscle relaxants
Eg: baclofen.
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- Check that the indication is still relevant.
- Review indication and dose.
- If recently started, does this coincide with increase in drowsiness.
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- Reduce dose or withhold if possible.
- Review on ward round.
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Parkinsonian medicine
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- These are time critical medicines.
- Check that the correct dose, formulation and times are prescribed.
- Is the dose too much or too little?
- Be aware of medicines that are contraindicated in Parkinson’s, eg: metoclopramide, prochlorperazine, haloperidol.
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- These are time critical medicines. Ensure that all staff caring for the patient are made aware.
- Refer to patients usual Parkinson’s consultant.
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