Important: Formulation and dosage details
Formulation:
Injection (adrenaline 1 in 100,000 (22 micrograms), articaine 88mg/2·2mL cartridge)
test announcement
24/02/22 Prilocaine hydrochloride hyperbaric solution for injection 2% (hospital use only - restricted to anaesthetists) added.
The maximum safe local anaesthesia doses are as follows:
Drug |
Maximum safe dose |
Lidocaine |
3mg/kg |
Lidocaine (with adrenaline/epinephrine) |
7mg/kg |
Bupivacaine |
2mg/kg |
Bupivacaine (with adrenaline/epinephrine) |
2mg/kg |
Levobupivacaine |
2mg/kg |
Infusion (epidural) 250mg/250mL (0·1%) in sodium chloride 0·9%
Solution for injection 0.25% 10ml ampoules
For spinal anaesthesia.
Solution for injection (Marcain Heavy®) 0.5%
Infusion in sodium chloride 0·9% (250mL) unlicensed
Solution for injection (Xylocaine®) (lidocaine 1%, adrenaline 1 in 200,000), (lidocaine 2%, adrenaline 1 in 200,000)
Solution for injection 1% 500mg/50mL
Hyperbaric solution for injection 2% (hospital use only - restricted to anaesthetists)
As per SMC 665/10: spinal anaesthesia.
SMC restriction: for use in spinal anaesthesia in ambulatory surgery settings such as day surgery units.