Important: Therapy notes
- If the patient is already on an ACE inhibitor, it should be stopped for 36 hours before initiating sacubitril/valsartan to minimise the risk of angioedema.
Important: Formulation and dosage details
Formulation:
Tablets 24mg/26mg, 49mg/51mg, 97mg/103mg (Entresto®) (s)
Dosage:
As per SMC 1132/16: in adult patients for treatment of symptomatic chronic heart failure with
reduced ejection fraction.