Anti-gonadotrophin releasing hormones (Formulary)

RELUGOLIX, ESTRADIOL AND NORETHISTERONE ACETATE - (First line)

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Film-coated tablets (Ryeqo) relugolix 40mg, estradiol 1mg, norethisterone acetate 0·5mg (specialist initiation only)

Dosage:

As per SMC 2442: treatment of moderate to severe symptoms of uterine fibroids in adult women of reproductive age.
SMC restriction: for use in patients who have failed or are unsuitable for conventional therapies (first line treatments), such as tranexamic acid, hormonal contraceptives and intrauterine delivery systems. 

Editorial Information

Document Id: F195