Important: Therapy notes
MHRA advice:Â Aminoglycosides (gentamicin, amikacin, tobramycin, and neomycin): increased risk of deafness in patients with mitochondrial mutations (January 2021) (www.gov.uk).
Important: Formulation and dosage details
Formulation:
Dosage:
Follow local hospital guidelines, monitor drug levels, see:
- gentamicin prescribing, administration and monitoring chart
- gentamicin dose calculator
- Policy for use of intravenous gentamicin as part of the management of infective endocarditis in adults
- For surgical prophylaxis – see dosing table and give as a single dose (no monitoring).