Important: Therapy notes
MHRA advice: Quinine: reminder of dose-dependent QT-prolonging effects; updated medicine interactions (November 2017) (www.gov.uk).
MHRA advice: Quinine: not to be used routinely for nocturnal leg cramps (December 2014) (www.gov.uk).
- Monitor patients closely during the early stages for adverse effects as well as for benefit. After an initial trial of 4 weeks, stop treatment if there is no benefit. Interrupt treatment at intervals of approximately 3 months to assess the need for further quinine treatment.