Vitamin B group (Formulary)

Important: Formulation and dosage details

Formulation:

Tablets 50mg, 100mg

Dosage:

• Mild deficiency: 25mg daily
• Severe deficiency: 200mg to 300mg daily in divided doses.
• Patients with alcohol dependence: should be prescribed oral thiamine 200mg to 300mg daily in divided doses:
  • before planned withdrawal of alcohol
  • during acute withdrawal of alcohol
  • for up to 12 months after acute withdrawal of alcohol, indefinitely in some cases
  • for patients not undergoing alcohol withdrawal but at high risk of developing Wernicke's encephalopathy.

Important: Formulation and dosage details

Formulation:

Tablets 10mg, 50mg

Dosage:

• Deficiency: 20 to 50mg up to 3 times daily.
• Isoniazid induced neuropathy:
  • Prophylaxis: 10mg daily
  • Treatment 50mg 3 times daily. 
• Idiopathic sideroblastic anaemia: 100 to 400mg daily in divided doses.

Notes:

• The use of pyridoxine in premenstrual syndrome off-label is of doubtful value.
• Overdosage induces toxic effects.

Important: Formulation and dosage details

Formulation:

High potency injection intravenous, intramuscular

Dosage:

• Guidance:
  • Pabrinex shortage: Specialist Pharmacy Service: Prescribing and using thiamine in patients at risk of refeeding syndrome
  • Unplanned alcohol withdrawal guideline.
  • For the administration in primary care settings refer to the PGD.

Important: Formulation and dosage details

Formulation:

Vitamin B compound strong tablets nicotinamide 20mg, pyridoxine hydrochloride 2mg, riboflavin 2mg, thiamine hydrochloride 5mg (Restricted: Hospital use only)

Dosage:

• For refeeding syndrome as per guideline: Refeeding policy
• Specialist Pharmacy Service: Prescribing and using thiamine in patients at risk of refeeding syndrome

Prescriptions are for a maximum of one month.