Transdermal oestrogen with cyclical progestogen (Formulary)

Important: Formulation and dosage details

Formulation:

Gel (Oestrogel® Pump-Pack 0.06%) 750 microgram/actuation

Dosage:

Apply 1.5mg once daily continuously, increased if necessary up to 3 mg after 1 month continuously, to be applied over a large area, to be used with cyclical progestogen for at least 12 days of each cycle in women with a uterus.  If switching from cyclical HRT, start at end of regimen; otherwise start at any time.

Important: Formulation and dosage details

Formulation:

Patches (Evorel® Sequi) estradiol 50 micrograms/24 hours patches plus estradiol 50 micrograms, norethisterone 170 micrograms/24 hours patches

Dosage:

1 estradiol-only patch to be applied twice weekly for 2 weeks followed by 1 estradiol/ norethisterone patch twice weekly for 2 weeks; subsequent courses are repeated without interval.

Important: Formulation and dosage details

Formulation:

Patches Femseven® Sequi patches are discontinued at present see: British Menopause Society update on HRT supply for suggested alternatives.