Long-acting antimuscarinic bronchodilator (LAMA) in asthma (Formulary)

TAM (Treatments and Medicines) NHS Highland
NHS Highland

Tiotropium solution for inhalation (Spiriva® Respimat®) has been accepted by SMC as add-on maintenance bronchodilator treatment in adult patients with asthma at Step 4 who are currently treated with the maintenance combination of inhaled corticosteroids (800 micrograms or more of budesonide per day or equivalent) and long-acting beta2 agonists and who experienced one or more severe exacerbations in the previous year.

TIOTROPIUM

Therapy notes

Formulation and dosage details

Formulation:

PREFERRED: Soft Mist Inhaler (SMI) These are more environmentally friendly than MDIs and should be considered first line providing that the patient shows good inhaler technique with the chosen device.

  • Solution for inhalation cartridge (Spiriva® Respimat®) 2·5 micrograms/metered inhalation

Dosage:

Asthma at Step 4, by inhalation of aerosol, 5 micrograms (2 puffs) once daily.

Editorial Information

Document Id: F348